She was “shaking” and otherwise “acting like she was suffering from a seizure,” a source told E! News.
The raven-haired beauty, who handlers revealed is now seeking help for stress and “exhaustion,” was doing “whip-its,” TMZ.com reported online.
PHOTOS: CELEBS WHO'VE GONE TO REHAB
The gaseous canisters of nitrous oxide, inhaled from whipped cream dispensers, send users into a state of other-worldliness.
Friends have watched with increasing worry the 49-year-old “Ghost” star’s downward spiral — and stunning weight loss that has left her looking frail and gaunt.
People.com reports that a battle with prescription drug use was among the reasons her marriage to 33-year-old actor Ashton Kutcher collapsed.
“It was a sticking point for Ashton,” a source told the mag. “He wanted her to take care of herself and get a hold of things, and she wouldn’t.”
“Her family and friends have been really worried,” the source said of Moore, whose first marriage to Bruce Willis, the father of her three daughters, also ended in divorce.
“Demi is a mess,” a friend told People.com.
“Really, it was over the last year her friends saw a change” another source said. “She wasn’t sleeping as well, didn’t seem to be eating and looked really gaunt.”
It all came crashing down for the child of two alcoholics Monday night, when paramedics rushed to Moore’s Beverly Hills mansion at 10:49 p.m. and whisked her to a nearby hospital.
Eldest daughter Rumer Willis, 23, rushed to Moore’s side and was photographed looking visibly distraught as she smoked and spoke on a cell phone outside the hospital.
Moore’s publicist declined to comment on the reports of substance abuse.
This is Moore’s second-known stint in rehab. She sought help during her Brat Pack heyday after director Joel Schumacher threatened to cut her from the seminal coming-of-age flick “St. Elmo’s Fire,” People reported.
“I remember she had a substance abuse problem. That was in the ’80s. But she was beautiful and charming and ragingly ambitious,” Michael Levine, Moore’s publicist at the time, told The News Wednesday.
“I think the issues of addiction are very complicated matters. You never ever recover fully.
You’re always recovering,” Levine said. “Stress also exacerbates issues in people’s lives.”
With her old demons apparently resurfacing, Moore has dropped out of her most recent film project, the Linda Lovelace biopic “Lovelace.”
She was set to play feminist icon Gloria Steinem in a small-but-critical role filming next week, sources said.
“We can advise she is no longer doing the movie,” publicist Carrie Gordon told The News.